$98.00 – $167.00
Tadalafil is the generic name of Cialis. It comes in tablet form for the treatment of Erectile Dysfunction under the name of Cialis. Tadalafil is a medication that relaxes the smaller muscles in the body.
strengths: 20mg, 10mg, 5mg
Tadalafil is an international (non-proprietary) name for a drug substance developed by the pharmaceutical company Eli Lilly, USA. The trade name of the proprietary drug is Cialis. The drug appeared on the market in 2003 and quickly gained popularity in many countries of the world, thanks to its efficiency and unique properties.
Cialis, with tadalafil included in it, refers to the pharmacological group of medicines of potency regulators. It is a selective inhibitor of PDE 5. It prevents phosphodiesterase in suppressing the synthesis of cGMP, which leads to relaxation of smooth muscles of the arteries and increased blood filling of the cavernous bodies of the penis. As a result, there is a strong and prolonged erection.
Tadalafil is a part of not only the original Cialis, but also various generics, which makes it affordable for people with different income levels. Tadalafil generics have an international non-proprietary name, either patented or modified, and are produced predominantly in India.
Description Of Cialis Tadalafil
It is a solid crystalline substance, practically insoluble in water and slightly soluble in ethyl alcohol. Produced in the form of tablets of almond-shaped yellow color, covered with a film membrane.
sodium lauryl sulfate;
Dosage of the drug with Cialis tadalafil – 2,5, 5, 20, 40 mg. On each tablet, on one side, digits indicating the dose of the active substance are engraved. The package contains the lot number and serial number.
Indication for taking medication is erectile dysfunction. Cialis Tadalafil has a symptomatic effect directly on the sexual organ of a man. Like other inhibitors of PDE 5, it is effective only with sufficient sexual stimulation.
After you have taken the drug, it is quickly absorbed by the body by absorption in the digestive tract.
Parallel ingestion of food or alcohol does not affect the process of assimilation of the active substance. The drug reaches a maximum concentration in the body on average – from 30 minutes to 6 hours.
Sexual intercourse is possible at least 16 minutes. Depending on the degree of erectile dysfunction and the characteristics of the body, this time can be increased to 30 minutes or more.
Feature of Cialis Tadalafil, in contrast to its analogs, is a long-term effect on the body up to 36 hours. For comparison: sildenafil (Viagra) – 6 hours, vardenafil (Levitra) – 10 hours.
The long range of the drug allows a man to be more comfortable with the planning of sexual intercourse. This removes psycho-emotional tension and harmonizes the relationships of partners.
Tadalafil is metabolized in the liver. Excretion is carried out through the intestine and in small quantities with urine.
The medicine is taken once a day at any time, regardless of food intake. The tablet should be washed down with a small amount of water.
The recommended dose of tadalafil is 20 mg., Including those over 65 years of age. Depending on the tolerability of the drug, the dose may vary from 2.5 mg. up to 40 mg. It should be remembered that a day can only take one tablet. Therefore, you can adjust the dose only the next day.
With functional violations of the liver in a mild or moderate degree, the dose of tadalafil is 10 mg.
With moderate renal failure – the initial dose of 5 mg. per day or 10 mg. once in 48 hours. With serious liver and kidney disease from taking the drug should be discarded.
It is not desirable to combine with other PDE 5 inhibitors. In this case, there may be an increase in side effects, as well as the occurrence of priapism (a prolonged and painful erection).
It cannot be used in diseases and indicators:
hypersensitivity to the active substance;
simultaneous intake with organic nitrates;
treatment with alpha-blockers;
severe hepatic and renal insufficiency;
diseases of the cardiovascular system (unstable angina, heart rhythm disturbances, myocardial infarction and stroke, transferred not later than 6 months);
children under the age of 18;
degenerative diseases of the retina;
anatomical curvature of the penis;
propensity to priapism.
Doctors strongly recommend not taking tadalafil to people with diseases included in the list of contraindications. Therefore, for effective and safe treatment should strictly follow the instructions for the use of tadalafil.
Among the reviews about the drug, positive ones predominate. Patients and doctors note the high efficacy and good tolerability of the drug. Tadalafil has numerous fans because of the duration of the action and the ability to combine it with food and alcohol.
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Comments on shortcomings are discussions on the high cost of the original and some side effects.
Tadalafil is a part of preparations of different types and forms. They differ in the way the drug is used, the dosage, the price, the manufacturer.
The tablets Cialis 20 mg (USA) and Tadalafil tablets 20 mg (India) instructions for use are the same. But the price of the original product and generic varies considerably.
To develop, test and implement the Cialis market, Eli Lilly has spent a large amount of money. And generics are produced by pharmaceutical companies using ready-made technology. Therefore, at much lower costs, a drug with the same effect as the original agent is created.
But despite the fact that tadalafil is included in the composition of Cialis, and generic, there are differences. The composition of the auxiliary components is likely to be very different, and the active substance will not be sufficiently purified and have different impurities. This explains the more side effects from generics.
Depending on the dosage of tadalafil, the price is also different. In the instructions, the recommended dosage is 20 mg., But there are customers and 2.5 mg. and by 40 mg. The price of tadalafil increases as a percentage of the increase in the dose of active substance in the tablet.
traditional tablets that need to be washed down with water;
tablets for resorption or chewing;
gel with fruit taste.
Instructions for the use of tadalafil in the form of traditional tablets – the standard. Take them recommended in a dosage 1 time a day, washing down with a small amount of water.
Tablets for resorption or chewing in the application are more convenient. They can be accepted at any time, regardless of the circumstances: at work, in transport or on the way to the meeting place.
Gel with tadalafil according to the instructions for use is faster than tablets. The gel is taken orally and the absorption of the active substance occurs in the mouth. Thus, it enters the bloodstream faster, reducing the time between taking the drug and the possibility of having a sexual intercourse.
The closest analogues of Cialis are Viagra (sildenafil) and Levitra (vardenafil). They are also inhibitors of PDE-5. Each of these drugs has its own distinctive feature that makes them popular with their fans. Which is better: Cialis, Viagra or Levitra is a matter of preference. Many online pharmacies offer to buy these products one by one to choose the option that is most suitable.
Prices may vary depending on the country of the manufacturer, the amount of transportation and other costs, as well as the mark-ups of pharmacy companies.
Cialis and its generics have a fairly wide range of various ailments.
Among them are the following:
painful sensations in the back, less often in the muscles of the chest and limbs;
headache and dizziness;
redness of the conjunctiva and pain in the eyes;
nausea, diarrhea, bloating;
tides of blood to the head, blood from the nose;
sudden spontaneous erection;
dryness of mucous membranes;
itching and rashes on the skin;
decrease or increase in blood pressure.
It should be noted that the strength of side effects depends on the dosage of tadalafil. Therefore, if you experience any ailments, you should reduce it.
When testing the drug in healthy men at a dose many times higher than normal, the side effects were manifested in the same way as with normal dosage. In case of an overdose, symptomatic standard treatment is used.
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