$33.00 – $305.00
Stimulant of the intestinal peristalsis. Its also assigned in cases of: distention, overeating, vomiting, heartburn, flatulence, a feeling of overflow of the stomach.
Strengths : 5mg, 10mg
Pharmacologic Class: Dopamine Antagonist
Domperidone is a medicine that increases the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson’s Disease.
Domperidone Tablets contain active ingredient called Domperidone and belongs to a class of medicine called
This medicine is used in adults and in children to treat nausea (feeling sick) and vomiting (being sick).
2. What you need to know before you take Domperidone Tablets
Do not take Domperidone Tablets if:
• you are allergic to domperidone or any of the other ingredients of this medicine (listed in section 6)
• you have a moderate or severe liver disease
• your ECG (electrocardiogram) shows a heart problem called “prolonged QT corrected interval”
• you have or had a problem where your heart cannot pump the blood round your body as well as it should
(condition called heart failure)
Warnings and Precautions:
Talk to your doctor or pharmacist before taking Domperidone if you:
– suffer from liver problems (liver function impairment or failure) (see “Do not take Domperidone Tablets if”)
– suffer from kidney problems (kidney function impairment or failure). It is advisable to ask your doctor for
advice in case of prolonged treatment as you may need to take a lower dose or take domperidone less often,
and your doctor may want to examine you regularly.
Domperidone may be associated with an increased risk of heart rhythm disorder and cardiac arrest. This risk
may be more likely in those over 60 years old or taking doses higher than 30mg per day. The risk also
increases when domperidone is given together with some drugs. Tell your doctor or pharmacist if you are
taking drugs to treat infection (fungal infections or bacterial infection) and/or if you have heart problems or AIDS/
HIV (see section other medicines and Domperidone Tablets).
Domperidone should be used at the lowest effective dose in adults and children.
While taking domperidone, contact your doctor if you experience heart rhythm disorders such as palpitations,
trouble breathing, loss of consciousness. Treatment with domperidone should be stopped.
Other medicines and Domperidone tablets:
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Do not take Domperidone Tablets if you are taking medicine to treat:
• fungal infections such as azole anti-fungals, specifically oral ketoconazole, fluconazole or voriconazole
• bacterial infections, specifically erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine
(these are antibiotics)
• heart problems or high blood pressure (e.g., amiodarone, dronedarone, quinidine, disopyramide, dofetilide,
sotalol, diltiazem, verapamil)
• psychoses (e.g., haloperidol, pimozide, sertindole)
• depression (e.g., citalopram, escitalopram)
• gastro-intestinal disorders (e.g., cisapride, dolasetron, prucalopride)
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For domperidone, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to domperidone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Some other allergies (e.g., mequitazine, mizolastine)
malaria (in particular halofantrine)
parkinson’s disease (e.g., levodopa)
AIDS/HIV (protease inhibitors)
cancer (e.g., toremifene, vandetanib, vincamine)
Children—Studies on domperidone have been done only in adult patients, and there is no specific information comparing use of domperidone in children with use in other age groups.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing the use of domperidone in the elderly with use in other age groups.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving domperidone, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
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